Shingles Vaccine Can Reduce Risk of Dementia
Syllabus: GS 2/Health
In News
- A study in Wales suggests that the shingles vaccine may reduce the likelihood of new dementia diagnoses by about 20% over seven years.
- Shingles (Herpes Zoster) is a viral infection caused by the Varicella-Zoster Virus (VZV), the same virus that causes chickenpox.
Dementia
- It is a group of diseases that affect memory, thinking, and daily activities, primarily in older adults, though not everyone will develop it with age.
- Common forms of dementia include Alzheimer’s disease, vascular dementia, dementia with Lewy bodies, and frontotemporal dementia.
- Risk factors include age (65+), high blood pressure, diabetes, obesity, smoking, excessive alcohol use, physical inactivity, social isolation, and depression.
- Dementia is caused by diseases that damage brain cells, leading to cognitive decline beyond normal aging.
- It can also arise from strokes, infections, alcohol abuse, or physical brain injuries.
- Impacts: It has physical, psychological, social, and economic impacts on individuals, carers, families, and society.
- Treatment : While there is no cure for dementia, treatments like physical activity, brain-stimulating activities, and medications (e.g., cholinesterase inhibitors, NMDA antagonists, blood pressure control) can help manage symptoms.
- Finding of recent study : The research, published in Nature, found that people eligible for the shingles vaccine (based on their birth date) had a lower risk of developing dementia compared to those who were ineligible.
- This effect was more pronounced in women than men
Source :TH
Semaglutide
Syllabus: GS2/Health
Context
- A recent study found that oral semaglutide (Rybelsus) reduces the risk of heart attacks, strokes, and cardiovascular death by 14%.
About
- Semaglutide is a GLP-1 receptor agonist (GLP-1RA) is to achieve a significant reduction in cardiovascular risk, was approved in 2021 for weight management in people with obesity and conditions like type 2 diabetes.
- The trial focused on reducing major adverse cardiovascular events (MACE) in people with type 2 diabetes, cardiovascular disease (CVD), and chronic kidney disease (CKD).
- The study found that oral semaglutide significantly reduced MACE compared to a placebo.
- Placebo is used in studies to compare the effects of a new treatment to a non-active treatment.
What is Diabetes? – Diabetes is a chronic medical condition where the body has trouble regulating blood sugar (glucose) levels. – It occurs when the body either doesn’t produce enough insulin (a hormone that helps regulate blood sugar) or doesn’t effectively use the insulin it produces. – There are two main types: 1. Type 1 Diabetes: The body doesn’t produce insulin at all, and it typically develops in childhood or adolescence. 2. Type 2 Diabetes: The body doesn’t use insulin properly (insulin resistance), often due to lifestyle factors, and usually develops in adults. – Managing Diabetes: 1. If not managed, diabetes can lead to serious health issues such as heart disease, kidney problems, and nerve damage. 2. Managing diabetes typically involves a combination of diet, exercise, medication, and regular blood sugar monitoring. |
Source: TH
Time Use Survey
Syllabus :GS 2/Governance/GS3/Economy
In News
- The Time Use Survey (TUS) 2024 revealed significant data on how people in India allocate their time across various activities.
Time Use Survey
- The National Statistics Office (NSO) under the Ministry of Statistics and Programme Implementation (MoSPI) conducted the first all-India Time Use Survey (TUS) from January to December 2019, and the second survey for 2024 was released in February 2025.
- It provides data on time spent on paid and unpaid tasks, learning, socializing, leisure, and self-care activities.
Do you know ? – India, alongside countries like Australia, Japan, and the USA, conducts the National Time Use Survey to analyze the participation of men and women in various activities. |
Objectives
- It aims to assess the participation of men and women in paid and unpaid activities, such as caregiving, volunteer work, and domestic chores.
- It aids in policy formulation, planning, and decision-making by government departments, organizations, and researchers.
Recent findings
- Delhi residents spend the most time on work-related activities, averaging 563 minutes daily, far surpassing the national average of 440 minutes.
- Goa follows closely with 536 minutes, showing a notable increase from 2019.
- The survey highlights a gender gap in unpaid domestic services, with women dedicating 289 minutes daily compared to men’s 88 minutes.
- Learning activities have slightly declined, with the national average dropping from 424 minutes in 2019 to 414 minutes in 2024. Andhra Pradesh and Tamil Nadu remain high in learning time.
- Socializing and community participation show varying trends across states, with Nagaland reporting increased social engagement.
- Leisure activities have risen nationwide, with Uttarakhand seeing a notable increase.
- Self-care time, including sleep and hygiene, has decreased nationally, with some states like Meghalaya and Jammu & Kashmir showing an increase.
Source :IE
NAFTA (North American Free Trade Agreement)
Syllabus: GS2/ International, GS3/ Economy
Context
- In an effort to advance a trade agreement with the United States and avoid 26% reciprocal tariffs, India’s Ministry of Commerce and Industry has expanded its NAFTA division.
North American Free Trade Agreement (NAFTA)
- The North American Free Trade Agreement (NAFTA) was a trilateral trade pact among the United States, Canada, and Mexico, effective from 1994 to 2020.
- It created one of the world’s largest free trade zones, eliminating tariffs and reducing trade barriers to promote economic integration.
- In 2020, NAFTA was replaced by the United States-Mexico-Canada Agreement (USMCA) with updated provisions on digital trade, labor standards, and environmental regulations.
Challenges in India-US Trade Talks
- Data Localisation Demands: The U.S. Trade Representative (USTR) has raised concerns about India’s data localisation requirements, which compel banks and payment service providers to store data within India.
- Intellectual Property (IP) Concerns: India has been placed on the USTR’s Priority Watch List due to;
- Lack of specific trade secret protection laws.
- Lengthy patent approval processes.
- Inconsistent enforcement of IP laws.
- Labour and Environmental Standards: India has yet to conclude a comprehensive trade agreement with any Western country, primarily due to divergent positions on;
- Labor rights enforcement mechanisms.
- Environmental sustainability standards demanded by developed countries.
Source: IE
22nd Amendment to the U.S. Constitution state
Syllabus: GS2/ International issues
Context
- The 22nd Amendment to the U.S. constitution was in the spotlight after the U.S. President Donald Trump made remarks on a two-term limit for American Presidents.
22nd Amendment to the U.S. Constitution
- The 22nd Amendment to the US Constitution says that no one can be elected more than twice as President.
- The Amendment was ratified in 1951, after President Franklin D Roosevelt had been elected four consecutive times, from 1932 to 1944.
- If someone has served as President for more than two years of another’s term (for example, a Vice President who became President due to the President’s death or resignation), they can only be elected once.
- Thus, effectively, the maximum U.S. Presidential tenure can be 10 years (two years as a successor plus two full terms).
Source: TH
MoSPI Released “Women and Men in India 2024” Report
Syllabus: GS3/ Economy
In Context
- The Ministry of Statistics and Programme Implementation (MoSPI), released the 26th edition of its publication titled “Women and Men in India 2024: Selected Indicators and Data”.
About
- The publication offers a comprehensive overview of the gender landscape in India, presenting selected indicators and data across key areas like population, education, health, economic participation, and decision-making, all sourced from various Ministries/ Departments/Organizations.
Some Key Highlights of the Publication
- Education: The Gender Parity Index (GPI) for enrolments at both primary and higher secondary levels increased in FY24 compared to FY23 and FY22, indicating more girls being enrolled in school.
- At the upper primary and elementary levels, the enrolment numbers were nearly equal for both boys and girls.
- Labour Force Participation: The Labour Force Participation Rate (LFPR) for women aged 15 years and above saw a significant improvement from 49.8% in 2017–18 to 60.1% in 2023–24.
- This reflects growing inclusion of women in the workforce and economic activity.
- Financial Inclusion: Women owned 39.2% of all bank accounts in India as of the latest data. They contributed 39.7% to total deposits in banks.
- Women’s presence is most prominent in rural areas, where they make up 42.2% of account holders.
- Entrepreneurship & Economic Independence: The number of female-headed proprietary establishments across manufacturing, trade, and services has been rising consistently between 2021–22 and 2023–24.
- Startups with at least one woman director (DPIIT-recognized):
- In 2017: 1,943 startups
- In 2024: 17,405 startups
- This is more than an 800% increase in 7 years.
- Startups with at least one woman director (DPIIT-recognized):
- Political Participation: Female voter turnout has seen variations over the years, rising to 67.2% in 2019, followed by a modest dip to 65.8% in 2024.
- Violence against Women: Nearly 31.9% of married women aged 18 to 49 in India report experiencing spousal violence, with the highest prevalence observed in Karnataka (48.4%), Bihar (42.5%), and Manipur (41.6%).
Source: AIR
Hadean Protocrust
Syllabus: GS3/Science and Technology
Context
- A new study questions the assumption that Earth’s chemical signatures post Hadean protocrust appeared only after subduction began.
About
- The Hadean protocrust refers to Earth’s first crust formed during the Hadean eon, which spanned from about 4.6 billion to 4 billion years ago.
- This eon marks the time right after the formation of the Earth, when the planet was still very hot and largely molten.
- During this time, the Earth’s surface was molten and bombarded by space rocks.

- Volcanic Activity: Frequent volcanic eruptions and asteroid bombardment shaped the surface.
- Conditions: Hot, inhospitable with little to no liquid water and a volcanic gas-dominated atmosphere.
- Thicker parts of the crust gradually formed the first continents, which moved on the asthenospheric mantle.
- Plate tectonics started as plates drifted, slid over, or dove under each other.
- These movements left distinct chemical signatures in the crust, helping scientists study plate tectonics.
- A new study questions the assumption that these signatures appeared only after subduction began.
- Researchers suggest that these signatures existed in the Hadean protocrust.
- This finding challenges a key idea in geology and needs validation by independent research.
Source: TH
CAPTCHA
Syllabus: GS3/ Science and Technology
Context
- CAPTCHA (Completely Automated Public Turing test to tell Computers and Humans Apart) is a key security tool that has transformed how websites protect user accounts and data.
What is CAPTCHA?
- CAPTCHA is a type of challenge–response test designed to distinguish human users from automated bots.
- It typically involves tasks that are easy for humans but difficult for machines to complete.
- Background: CAPTCHA is based on an idea called the Turing test. This was proposed by British mathematician Alan Turing back in the 1950s.
- CAPTCHA was introduced in the early 2000s as a response to rising internet abuse by bots, including fake registrations, spam, and data scraping.
- The term CAPTCHA was coined in 2003 by Luis von Ahn, Manuel Blum, Nicholas J. Hopper, and John Langford at Carnegie Mellon University.
Source: TH
Exercise INDRA 2025
Syllabus: GS3/Defence
Context
- The 14th edition of the India-Russia bilateral naval exercise, INDRA 2025, was recently concluded.
About
- The exercise included a wide range of activities and structured drills designed to enhance interoperability towards countering common maritime threats.
- The INDRA series of exercises have been a cornerstone of India-Russia Defence relations since its inception in 2003 and both countries recognise the importance of maritime security and the need for a collaborative approach to counter common threats and concerns.
Source: PIB
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